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Apostolos Mourtzinos, MSc

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  • Liknedin

Hello, I am Apostolos Mourtzinos. Welcome to my personal website! I am a researcher in the field of biomedical sciences. Within this website, you will find comprehensive information about my career, including my educational background, research experience, and notable achievements. I have dedicated myself to the pursuit of scientific knowledge in the realm of biomedical sciences, and my website provides a glimpse into the projects I have been involved in, the research questions I have explored, and the methodologies I have employed.

Research Interests

During my academic career I have been exposed to multiple research topics in the fields of biology and biomedical sciences, varying from researching mechanisms of plant immunity to studying macromolecular interactions in human diseases. Currently my research interests concern the role of human LINE-1 retrotransposons in healthy aging and disease. In order to improve our understanding of how activation of LINE-1s contribute to disease, we employ affinity capture and mass spectrometry along with other biochemical techniques to identify interactions responsible for disease progression and to dissect its mechanisms of action. Despite my focus on LINE-1 biology, I have been involved in several other projects, including the characterization of affinity captured DNAJB1-PRKACA protein interactome in fibrolamellar hepatocellular carcinoma, a pediatric liver cancer, whose oncogenesis is driven by a genetic fusion event between DNAJB1-PRKACA. 

Research Experience

  • Rockefeller University, New York City, Laboratory of Cellular and Structural Biology

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  • European Research Institute for the Biology of Aging, Groningen, The Netherlands​​, Laboratory of Macromolecules and Interactomes

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  • University Medical Center Groningen (UMCG), University of Groningen, The Netherlands, Department of Gastroenterology and Hepatology

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  • The University of Sheffield, United Kingdom, Department of Animal and Plant Sciences

 

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  • Biomedical Research Foundation Academy of Athens, Greece, Department of Fundamental Research 

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  • Agios Savvas General Hospital Against Cancer, Athens, Greece, Department of Cancer Cytogenetics

 

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